Table 4. Analyses of the relationship between abnormal coiling and adverse outcomes.
| PTB <37w | 5 min Apgar <7 | 1 min Apgar <7 | NICU admission | BW <2500g | SGA/FGR (all definitions) | CS | |
|---|---|---|---|---|---|---|---|
| Hypocoiling | |||||||
| Odds ratio (95% CI) | 1.68 (1.18, 2.39) | 4.45 (2.04, 9.71) | 3.18 (1.36, 7.43) | 2.24 (0.83, 6.04) | 2.06 (0.91, 4.70) | 1.65 (0.76, 3.58) | 2.82 (2.13, 3.73) |
| I2 | 0.00% (p = 0.800) | 78.6% (p = 0.00) | 62.5% (p = 0.069) | 74.9% (p<0.01) | 81.2% (p = 0.00) | 71.6% (p = 0.00) | 0.0% (p = 0.533) |
| No. of pregnancies | 2396 | 3982 | 1547 | 2123 | 2578 | 6150 | 4751 |
| Hypercoiling | |||||||
| Odds ratio (95% CI) | 2.48 (1.52, 4.06) | 1.97 (0.93, 4.18) | 0.80 (0.45, 1.43) | 1.56 (0.85, 2.86) | 3.69 (1.79, 7.64) | 4.31 (1.89, 9.79) | 3.55 (1.74, 7.26) |
| I2 | 43.0% (p = 0.135) | 78.5% (p = 0.00) | 0.00% (p = 0.707) | 32.4% (p = 0.193) | 78.9% (p = 0.00) | 84.3% (p = 0.00) | 82.0% (p = 0.00) |
| No. of pregnancies | 2275 | 3969 | 1550 | 2118 | 2781 | 6767 | 4820 |
Key: BW = birth weight, CS = caesarean section, FGR = fetal growth restriction, NICU = neonatal intensive care unit, PTB = pre-term birth, SGA = small for gestational age.