Figure 11.

Correlation of LLPS and diffusion characteristics in untreated cells. $K_{\alpha }$, α and CV of fibrillarin intensities in 12 Jurkat cells before ATP depletion: (a) CV values vs $\mathsf{\alpha }.$; (b) CV values vs $K_{\alpha }$; (c) CV values vs α_work. CV values were calculated for all pixel intensities within the footprint of individual cells (N = 12). p-values for the exponential regression are depicted in (b) and (c). No significant correlation was found in (a); (d) schematic representation of the impact of α_work on both $K_{\alpha }$ (Figure 9c) and LLPS (Figure 11c) that may create the correlation between $K_{\alpha }$ and LLPS (Figure 9b).