Algorithm 2 Predict Degree of Motor Fluctuation Severity

Input: Distribution of degree of change in UPDRS III score: $\left\{d_0,d_1,d_2,d_3\right\}$ Initialize $p_0,p_1,p_2,p_3$ to 0. if$\frac{{{\displaystyle \sum }}_{i=1}^3{d}_i}{d_0}>0.3$then set $p_0$ to N/A for$s=1to3$repeat $p_s=\frac{d_s}{{{\displaystyle \sum }}_{s=0}^3{d}_s}$ End for else if$\frac{{{\displaystyle \sum }}_{i=1}^3{d}_i}{d_0}\le 0.2$then set $p_0$ to 100% set $p_1,p_2$ and $p_3$ to N/A else $S=$ INC set $p_0,p_1,p_2$ and $p_3$ to N/A break end if $S=argma{x}_s{\left\{p_s\right\}}_{s=0:3}$ Output: Predicted degree of motor fluctuation severity ($S$) and ACUPDRS III percentage {$p_0,p_1,p_2,p_3\}$