TABLE 1.
RNA-seq analysis of transcript levels in B. abortus 2308 compared to the B. abortus rne-tnc straina
| Transcript level in B. abortus rne-tnc and BAB no. | BAB_RS no. | Log2 fold change | Description of gene product |
|---|---|---|---|
| Elevated | |||
| BAB_RS27990 | 2.5 | Hypothetical protein | |
| BAB2_0534 | BAB_RS28900 | 2.4 | Multicopper oxidase CueO |
| BAB1_0179 | BAB_RS16760 | 2.2 | Uroporphyrin-III c-methyltransferase |
| BAB1_0042 | BAB_RS16135 | 2.2 | Cytochrome c oxidase subunit IV |
| Decreased | |||
| BAB1_0393 | BAB_RS17810 | 4.4 | Fur family transcriptional regulator |
| BAB_RS17815 | 4.2 | Hypothetical protein | |
| BAB1_1579 | BAB_RS23450 | 4.2 | Membrane protein OmpW |
| BAB1_1460 | BAB_RS22885 | 3.5 | Divalent metal cation transporter MntH |
| BAB1_0308 | BAB_RS17400 | 3.0 | Dihydrorhizobitoxine desaturase |
| BAB1_0309 | BAB_RS17405 | 2.9 | Dihydropyrimidinase |
| BAB1_0313 | BAB_RS17425 | 2.9 | Dihydropyrimidine dehydrogenase subunit B |
| BAB1_0215 | BAB_RS16925 | 2.7 | Thiamine-phosphate pyrophosphorylase |
| BAB1_0214 | BAB_RS16920 | 2.5 | ABC transporter ATP-binding protein |
| BAB_RS28965 | 2.4 | Sugar transporter | |
| BAB1_0218 | BAB_RS16940 | 2.4 | Thiamine biosynthesis protein thio |
| BAB2_0348 | BAB_RS28030 | 2.3 | Major facilitator superfamily transporter |
| BAB1_0312 | BAB_RS17420 | 2.3 | Hypothetical protein |
| BAB2_0550 | BAB_RS28970 | 2.3 | Sugar ABC transporter permease |
| BAB2_0448 | BAB_RS28960 | 2.3 | Sugar ABC transporter permease |
| BAB1_0373 | BAB_RS17715 | 2.3 | ABC transporter substrate-binding protein |
| BAB1_0216 | BAB_RS16930 | 2.2 | Thiazole synthase |
| BAB2_0830 | BAB_RS30275 | 2.2 | Leu/Ile/Val-binding protein homolog 8 |
| BAB1_0219 | BAB_RS16945 | 2.2 | Phosphomethylpyrimidine kinase |
| BAB2_0277 | BAB_RS27685 | 2.2 | Glucose-methanol-choline oxidoreductase |
| BAB1_0967 | BAB_RS20555 | 2.2 | Aromatic hydrocarbon degradation protein |
| BAB2_0620 | BAB_RS29280 | 2.1 | Hypothetical protein |
| BAB1_0738 | BAB_RS19450 | 2.1 | Lactate permease |
| BAB_RS22440 | 2.1 | ATPase | |
| BAB1_0212 | BAB_RS16910 | 2.0 | ABC transporter permease |
| BAB1_0204 | BAB_RS16870 | 2.0 | Alcohol dehydrogenase |
| BAB2_0913 | BAB_RS30625 | 2.0 | Hypothetical protein |
| BAB2_0547 | BAB_RS28955 | 2.0 | Sugar-binding periplasmic protein |
| BAB1_1794 | BAB_RS24460 | 2.0 | Leu/Ile/Val-binding protein homolog 1 |
a
Shown are transcripts that exhibited ≥4-fold differential levels (i.e., log2 fold change ≥ 2) between the two strains.