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Percent change in bone mineral density from ACTIVE baseline to 43 months of ACTIVExtend in participants ≥80 years (intent-to-treat population). (A) Lumbar spine, (B) Total hip, and (C) Femoral neck. The ANCOVA model with missing data imputation by last observation carried forward was used for bone mineral density at each anatomical site. ∗P < 0.0001; †P < 0.01; ‡P < 0.05. ABL, abaloparatide; ALN, alendronate; PBO, placebo; SE, standard error.
