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. 2019 Dec 3;21(4):388. doi: 10.1080/15384047.2019.1699718

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© 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

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Figure 4. — Knockdown of GLUT4 reduces proliferation and metastasis of melanoma cells. (A) Western Blot confirmed that GLUT4 siRNA can significantly knockdown the expression of GLUT4. (B) MTT assay showed decreased proliferative ability in GLUT4 siRNA-transfected A375 and GLUT4 siRNA-transfected WM451 cells than that in NC cells. (C-D) Scratch and Transwell invasion experiments showed inhibited migration and invasion ability in A375 and WM451 cells after down regulation of GLUT4. ***P <0.001, **P < 0.01, *P < 0.05.