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. 2020 Feb 23;21(5):452–462. doi: 10.1080/15384047.2020.1727700

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 3. — Overexpression of miR-24-3p inhibits the resistance of PTX in PTX-resistant PCa cells.

(a) The level of miR-24-3p was measured in PCa tissues and normal samples by qRT-PCR. (b and c) The abundance of miR-24-3p was detected in PCa and PTX-resistant PCa cells by qRT-PCR. (d) The expression of miR-24-3p was measured in PC3-TXR and DU-145-TXR cells transfected with miR-24-3p or NC by qRT-PCR. The survival rate, IC50 of PTX (e), apoptosis (f), viability (g) and C-caspase 3 expression (h) were examined in PC3-TXR and DU-145-TXR cells transfected with miR-24-3p or NC by MTT assay, flow cytometry and western blot assays, respectively. *P < .05.