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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Expert Opin Ther Pat. 2019 Dec 19;30(1):39–55. doi: 10.1080/13543776.2020.1705783

Figure 8.

Figure 8.

The chemical structures of macrocyclic inhibitors of FXIa (27 and 28) claimed by Merck Sharp & Dohme Corp, US. Provided are the FXIa and PK Ki values (nM).