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. 2020 Aug 21;48(17):9478–9490. doi: 10.1093/nar/gkaa678

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Results of NEAR applied to the YLR301W gene. (A) The optimized profile {κ_i} is plotted (triangle markers) as a function of the codon position i, and compared to the naive estimates {1/r_i} (round marker). In panel (B), we compare the model-predicted density profile obtained using the inferred {κ_i} (lighter line) with the experimental normalized profile {r_i}. The inset shows the scatter plot between the two densities (for each codon i) demonstrating an excellent agreement between theory and experiments.