Table 4. Hemodynamic parameters after TAVR.
Overall (n=189) | Sapien XT (n=94) | Sapien 3 (n=95) | p value | |||
---|---|---|---|---|---|---|
In-hospital | ||||||
Mean pressure gradient (mmHg) | 11.3±4.2 | 11.4±4.5 | 11.2±4.0 | 0.788 | ||
Peak velocity (m/s) | 2.26±0.40 | 2.21±0.40 | 2.30±0.39 | 0.170 | ||
EOA* (cm2) | 1.86±0.58 | 2.07±0.61 | 1.70±0.49 | <0.001 | ||
23 mm THV | 1.69±0.50 | 1.96±0.57 | 1.51±0.35 | 0.001 | ||
26 mm THV | 1.94±0.60 | 2.08±0.64 | 1.80±0.54 | 0.039 | ||
29 mm THV | 2.08±0.60 | 2.48±0.53 | 1.92±0.56 | 0.052 | ||
EOAI* (cm2/m2) | 1.20±0.40 | 1.31±0.43 | 1.11±0.34 | 0.002 | ||
23 mm THV | 1.15±0.39 | 1.33±0.48 | 1.03±0.28 | 0.010 | ||
26 mm THV | 1.22±0.40 | 1.26±0.41 | 1.18±0.39 | 0.372 | ||
29 mm THV | 1.27±0.39 | 1.59±0.32 | 1.13±0.34 | 0.011 | ||
Prosthesis-patient mismatch | 25/157 (15.9) | 4/67 (6.0) | 21/90 (23.3) | 0.004 | ||
Severe | 1/157 (0.6) | 0/67 (0.0) | 1/90 (1.1) | 1.000 | ||
PVL>mild | 7/187 (3.7) | 7/93 (7.5) | 0/94 (0.0) | 0.007 | ||
1-month follow-up | ||||||
Mean pressure gradient (mmHg) | 12.5±4.5 | 12.7±4.8 | 12.2±4.3 | 0.615 | ||
Peak velocity (m/s) | 2.39±0.41 | 2.39±0.43 | 2.40±0.38 | 0.911 | ||
EOA* (cm2) | 1.72±0.49 | 1.86±0.57 | 1.60±0.37 | 0.010 | ||
23 mm THV | 1.54±0.42 | 1.67±0.50 | 1.43±0.32 | 0.083 | ||
26 mm THV | 1.81±0.46 | 1.92±0.58 | 1.70±0.26 | 0.069 | ||
29 mm THV | 2.04±0.76 | 2.63±0.44 | 1.80±0.75 | 0.216 | ||
EOAI* (cm2/m2) | 1.07±0.30 | 1.13±0.36 | 1.02±0.22 | 0.069 | ||
23 mm THV | 1.01±0.30 | 1.05±0.36 | 0.98±0.25 | 0.510 | ||
26 mm THV | 1.10±0.27 | 1.15±0.34 | 1.06±0.16 | 0.219 | ||
29 mm THV | 1.18±0.46 | 1.66±0.18 | 0.99±0.40 | 0.081 | ||
Prosthesis-patient mismatch | 22/101 (21.8) | 12/47 (25.5) | 10/54 (18.5) | 0.394 | ||
Severe | 2/101 (2.0) | 1/47 (2.1) | 1/54 (1.9) | 1.000 | ||
Ejection fraction (%) | 60.2±8.1 | 61.6±8.2 | 58.6±7.8 | 0.054 | ||
PVL>mild | 10/114 (8.8) | 10/60 (16.7) | 0/54 (0.0) | 0.001 | ||
Mitral regurgitation>mild | 4/113 (3.5) | 1/59 (1.7) | 3/54 (5.6) | 0.347 |
Values are presented as number of patients (%) or mean±standard deviation.
EOA = effective orifice area; EOAI = effective orifice area index; PVL = paravalvular leakage; TAVR = transcatheter aortic valve replacement; THV = transcatheter heart valve.
*Patients who underwent valve-in-valve procedure (n=5) were excluded from mean EOA/EOAI calculation.