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. 2020 Jul 28;50(10):907–922. doi: 10.4070/kcj.2020.0061

Table 4. Hemodynamic parameters after TAVR.

Overall (n=189) Sapien XT (n=94) Sapien 3 (n=95) p value
In-hospital
Mean pressure gradient (mmHg) 11.3±4.2 11.4±4.5 11.2±4.0 0.788
Peak velocity (m/s) 2.26±0.40 2.21±0.40 2.30±0.39 0.170
EOA* (cm2) 1.86±0.58 2.07±0.61 1.70±0.49 <0.001
23 mm THV 1.69±0.50 1.96±0.57 1.51±0.35 0.001
26 mm THV 1.94±0.60 2.08±0.64 1.80±0.54 0.039
29 mm THV 2.08±0.60 2.48±0.53 1.92±0.56 0.052
EOAI* (cm2/m2) 1.20±0.40 1.31±0.43 1.11±0.34 0.002
23 mm THV 1.15±0.39 1.33±0.48 1.03±0.28 0.010
26 mm THV 1.22±0.40 1.26±0.41 1.18±0.39 0.372
29 mm THV 1.27±0.39 1.59±0.32 1.13±0.34 0.011
Prosthesis-patient mismatch 25/157 (15.9) 4/67 (6.0) 21/90 (23.3) 0.004
Severe 1/157 (0.6) 0/67 (0.0) 1/90 (1.1) 1.000
PVL>mild 7/187 (3.7) 7/93 (7.5) 0/94 (0.0) 0.007
1-month follow-up
Mean pressure gradient (mmHg) 12.5±4.5 12.7±4.8 12.2±4.3 0.615
Peak velocity (m/s) 2.39±0.41 2.39±0.43 2.40±0.38 0.911
EOA* (cm2) 1.72±0.49 1.86±0.57 1.60±0.37 0.010
23 mm THV 1.54±0.42 1.67±0.50 1.43±0.32 0.083
26 mm THV 1.81±0.46 1.92±0.58 1.70±0.26 0.069
29 mm THV 2.04±0.76 2.63±0.44 1.80±0.75 0.216
EOAI* (cm2/m2) 1.07±0.30 1.13±0.36 1.02±0.22 0.069
23 mm THV 1.01±0.30 1.05±0.36 0.98±0.25 0.510
26 mm THV 1.10±0.27 1.15±0.34 1.06±0.16 0.219
29 mm THV 1.18±0.46 1.66±0.18 0.99±0.40 0.081
Prosthesis-patient mismatch 22/101 (21.8) 12/47 (25.5) 10/54 (18.5) 0.394
Severe 2/101 (2.0) 1/47 (2.1) 1/54 (1.9) 1.000
Ejection fraction (%) 60.2±8.1 61.6±8.2 58.6±7.8 0.054
PVL>mild 10/114 (8.8) 10/60 (16.7) 0/54 (0.0) 0.001
Mitral regurgitation>mild 4/113 (3.5) 1/59 (1.7) 3/54 (5.6) 0.347

Values are presented as number of patients (%) or mean±standard deviation.

EOA = effective orifice area; EOAI = effective orifice area index; PVL = paravalvular leakage; TAVR = transcatheter aortic valve replacement; THV = transcatheter heart valve.

*Patients who underwent valve-in-valve procedure (n=5) were excluded from mean EOA/EOAI calculation.