Table 2.
Adverse Event | Grade | |||||||
---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | |||||
N | % | N | % | N | % | N | % | |
Anemia | 15 | 51.7 | 5 | 17.2 | 1 | 3.4 | ||
Abdominal pain | 7 | 24.1 | 6 | 20.7 | 1 | 3.4 | ||
Hypokalemia | 5 | 17.2 | 2 | 6.9 | 3 | 10.3 | ||
Diarrhea | 8 | 27.6 | 1 | 3.4 | ||||
Fatigue | 3 | 10.3 | 4 | 13.8 | 1 | 3.4 | ||
Nausea | 5 | 17.2 | 1 | 3.4 | 2 | 6.9 | ||
Alkaline phosphatase elevation | 4 | 13.8 | 1 | 3.4 | 2 | 6.9 | ||
Aspartate aminotransferase elevation | 4 | 13.8 | 1 | 3.4 | 1 | 3.4 | ||
Cardiac troponin elevation | 3 | 10.3 | 2 | 6.9 | 1 | 3.4 | ||
Hypercalcemia | 5 | 17.2 | ||||||
Vomiting | 2 | 6.9 | 3 | 10.3 | ||||
Hyperphosphatemia | 1 | 3.4 | 3 | 10.3 | ||||
Abdominal distension | 2 | 6.9 | 1 | 3.4 | ||||
Alanine aminotransferase elevation | 1 | 3.4 | 1 | 3.4 | 1 | 3.4 | ||
Hypertension | 3 | 10.3 | ||||||
Hyponatremia | 1 | 3.4 | 2 | 6.9 | ||||
Hyperbilirubinemia | 1 | 3.4 | 1 | 3.4 | ||||
Hyperglycemia | 2 | 6.9 | ||||||
Dehydration | 2 | 6.9 | ||||||
Dry skin | 2 | 6.9 | ||||||
Dyspepsia | 2 | 6.9 | ||||||
Dyspnea | 1 | 3.4 | 1 | 3.4 | ||||
Edema limbs | 1 | 3.4 | 1 | 3.4 | ||||
Leukopenia | 2 | 6.9 | ||||||
Muscle weakness | 2 | 6.9 | ||||||
Neutropenia | 1 | 3.4 | 1 | 3.4 | ||||
Pain in extremity | 1 | 3.4 | 1 | 3.4 | ||||
Hypoalbuminemia | 1 | 3.4 | 1 | 3.4 | ||||
Hyperkalemia | 1 | 3.4 | 1 | 3.4 | ||||
Adrenal insufficiency | 1 | 3.4 | ||||||
Anorexia | 1 | 3.4 | ||||||
Arrhythmia | 4 | 13.8 | 1 | 3.4 | ||||
Back pain | 1 | 3.4 | ||||||
Cardiac troponin I elevation | 1 | 3.4 | ||||||
Chills | 1 | 3.4 | ||||||
Constipation | 1 | 3.4 | ||||||
Fever | 1 | 3.4 | ||||||
Flushing | 1 | 3.4 | ||||||
Gastritis | 1 | 3.4 | ||||||
Hand-and-foot syndrome/reaction | 1 | 3.4 | ||||||
Insomnia | 1 | 3.4 | ||||||
Lymphopenia | 1 | 3.4 | ||||||
Oral mucositis | 1 | 3.4 | ||||||
Myalgia | 1 | 3.4 | ||||||
Palpitations | 1 | 3.4 | ||||||
Pericardial effusion | 1 | 3.4 | ||||||
Thrombocytopenia | 1 | 3.4 | ||||||
Hypocalcemia | 1 | 3.4 | ||||||
Skin hyperpigmentation | 1 | 3.4 | ||||||
Taste alteration | 1 | 3.4 | ||||||
Urinary tract infection | 1 | 3.4 |