Table 4.
Relationship Between mRNA Expression of Molecular Markers and overall Survival
| Marker RNA Expression | No. of Patients | 5-Year Survival Probability (P ± SE) | Relative Risk | P Value |
|---|---|---|---|---|
| EGFR | ||||
| <7 | 35 | .64 ± 0.10 | 1 | |
| ≥7 | 13 | .63 ± 0.15 | 1.49 | .46 |
| N/A | 4 | – | ||
| ERCC1 | ||||
| <0.7 | 24 | .70 ± 0.10 | 1 | |
| ≥0.7 | 21 | .47 ± 0.21 | 1.08 | .88 |
| N/A | 7 | – | ||
| TS | ||||
| <2 | 24 | .70 ± 0.10 | 1 | |
| ≥2 | 19 | .65 ± 0.15 | 0.98 | .97 |
| N/A | 9 | – |
Abbreviations: EGFR = epidermal growth factor receptor; ERCC1 = excision-repair cross-complementation group 1 protein; N/A = not available; SE = standard error; TS = thymidylate synthase.