Fig. 1. HKDC1 expression regulates tumor growth in ENKTL cells.

a Different ENKTL cell lines were used for gene expression analysis of hexokinase, n = 4. *P < 0.05, vs MNCs group. b–g The SNK6 cells were infected by empty lentivirus control (CTL), HK2 (↑HK2) or HKDC1 (↑HKDC1) overexpression lentivirus, or HK2 (shHK2) or HKDC1 (shHKDC1) knockdown lentivirus, and the cells were used for biomedical analysis. b mRNA expression by qPCR, n = 4. c Protein quantitation by western blotting, n = 5. d Representative pictures for c. e Cell proliferation analysis by thymidine incorporation, n = 5. f [³H]-deoxyglucose uptake, n = 5. g Apoptosis analysis by TUNEL assay, n = 4. h Representative picture for g. *P < 0.05, vs CTL group; ^¶P < 0.05, vs shHK2 group. Data were expressed as mean ± SEM.