Table 1.
Frequency of PI3K pathway alterations in cancer.
| Cancer type | Altered genes | ||
|---|---|---|---|
| PIK3CA (%) | PTEN (%) | AKT1 (%) | |
| Breast cancer | 40 | 2–4 | 2–3 |
| Endometrial cancer | 68 | 43 | 3 |
| Lung cancer | 30 | 4 | 4 |
| Squamous cell carcinoma | 42.70 | 3 | 2 |
| Ovarian cancer | 68 | 19 | 27 |
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