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. 2020 Sep 24;10:15649. doi: 10.1038/s41598-020-72815-9

Table 2.

Kidney function parameters.

All patientsa(n = 665) Urea-to-creatinine ratiob
 < 61 (n = 221) 61–84 (n = 223)  > 84 (n = 221)
Pre-existent kidney function
Creatinine (µmol/L) 87 (84–91) 92 (87–97) A 88 (82–95) B 82 (77–88) B
Urea (mmol/L) 6.4 (6.2–6.7) 5.6 (5.1–6.2) A 6.1 (5.8–6.6) A 7.3 (6.8–8.1) B
Urea-to-creatinine ratio 71 (69–74) 57 (54–59) A 69 (67–73) B 89 (86–94) C
Kidney function upon presentation
Creatinine (µmol/L) 91 (88–95) 98 (91–109) A 92 (85–97) B 83 (79–92) B
Relative change in creatinine 1.03 (1.01–1.05) 1.05 (1.00–1.07) 1.02 (1.00–1.05) 1.02 (1.00–1.05)
Urea (mmol/L) 6.9 (6.6–7.4) 5.0 (4.8–5.5) A 6.6 (6.3–7.4) A 8.8 (8.2–9.4) B
Relative change in urea 1.05 (1.01–1.07) 0.91 (0.89–0.96) A 1.07 (1.04–1.13) B 1.15 (1.08–1.22) C
Urea-to-creatinine ratio 72 (70–75) 53 (51–54) A 72 (71–74) B 103 (100–105) C
Kidney function at discharge
Creatinine (µmol/L) 83 (81–88) 89 (83–94) A 84 (81–91) B 79 (74–87) B
Urea (mmol/L) 5.6 (5.4–6.1) 4.5 (4.3–5.0) A 5.6 (5.4–6.4) B 6.6 (6.4–7.4) B
Urea-to-creatinine ratio 66 (63–68) 50 (49–52) A 68 (66–70) B 88 (85–93) C

aData are presented as n (%) for categorical variables or median (95%CI) for continuous variables. Different letters in superscript represent significant differences between groups (p < 0.05).

bThe urea-to-creatinine ratio was calculated by dividing the serum urea (mmol/L) by the serum creatinine (µmol/L). To convert the presented urea-to-creatinine ratio in SI-units to conventional units (i.e. BUN and serum creatinine in mg/dL) divide the presented ratio by four.