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. 2020 Sep 24;9(9):84. doi: 10.1038/s41389-020-00268-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Treatment with 10 μM ISO for 48 h affected the morphologies of SMMC-7721 and SK-Hep1 cells, while pre-incubation with 100 μM ICI118,551 or YB-1 knockdown inhibited the changes in cell morphology. Scale bar: 100 μm. b Immunofluorescence assay to detect the epithelial marker E-cadherin and the mesenchymal markers N-cadherin and vimentin in SMMC-7721 cells following the indicated treatments. Scale bar: 100 μm. c Western blot analysis to detect the expression of E-cadherin, N-cadherin and vimentin in SMMC-7721 and SK-Hep1 with different treatment.