Table 1.

Patient features at inclusion and after 5 years.

	2012	2017	p
Ever smoker, n (%)	15 (41.7)	19 (59.4)	–
FVC%	106 (15.8)	110 (19.7)	0.437
DLCO%	85.2 (20.3)	78.2 (17.5)	0.122
RF, IU/mL	25.6 (12.6–60.4)	66.0 (15.9–224)	0.201
ACPA, U/mL	116 (10.8–604)	115 (1–428)	0.710
CRP, mg/L	6.55 (2.92–15.7)	2.70 (0.75–6.47)	0.005
ESR, mm/h	26 (16–37.2)	19 (7.25–30)	0.080
DAS28-CRP	5.24 (4.48–6.05)	2.25 (1.96–3.38)	< 0.001

Results are expressed as mean (SD) or median (Q1–Q3) where applicable.

FVC forced vital capacity, DLCO diffusion lung transfer of carbon monoxide, RF rheumatoid factor, ACPA anti-citrullinated peptide autoantibodies, CRP C reactive protein, ESR erythrocyte sedimentation rate.

The values of p < 0.05 are considered statistically significant.