Table 3.

Overlap of neuropsychiatric disease (NPD) interactomes and genes differentially expressed in NPDs with the cilia interactome.

NPD	NPD interactome size	p value of overlap	# Genes common to both interactomes	# Novel interactors common to both	# Genes differentially expressed in the disorder	# Genes differentially expressed in the cilia interactome	p value of overlap	# Differentially expressed novel genes
ADHD	406	1.20E−16	88	17	n/a	n/a	n/a	n/a
Alzheimer's disease	417	2.20E−24	104	19	1,103	106	4.70E−05	46
Autism spectrum disorder	53	2.20E−05	15	5	3,692	314	2.40E−04	119
Bipolar disorder	764	3.10E−29	163	31	1,188	101	3.40E−02	38
Major depressive disorder	974	3.70E−23	177	32	187	21	2.50E−02	8
Parkinson's disease	520	1.20E−20	112	18	2,487	258	6.20E−03	104
Schizophrenia	688	1.50E−16	125	26	1,320	118	5.60E−03	40
Intellectual disability	n/a	n/a	n/a	n/a	706	75	6.50E−03	32

The significance of the overlap along with the number of genes common to the NPD interactome/expression datasets and the cilia interactome are shown.