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. 2020 Sep 3;86(4):451–459. doi: 10.1007/s00280-020-04132-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Exploratory treatment–response analysis including glasdegib + decitabine treatment. The black dotted lines represent the survival functions, S(t) from the exploratory treatment–response final model with the 95% confidence interval of the predicted survival function in the shaded area by treatment arm. The solid lines are the observed OS data from the glasdegib + decitabine (pink), glasdegib + LDAC (green), and LDAC alone (blue) treatment arms. LDAC low-dose cytarabine, OS overall survival, S(t) probability of survival