Table 1.
Comparison of baseline characteristic between patients with juvenile idiopathic arthritis and healthy control
| Clinical characteristics | Case group (n = 33) | Control group (n = 20) | P value | |
|---|---|---|---|---|
| sJIA group (n = 20) | pJIA group (n = 13) | |||
| Age (y), mean ± SD | 7.36 ± 2.71 | 6.80 ± 2.23 | 6.56 ± 2.18 | 4.409 |
| Sex (male:female) | 13:7 | 8:5 | 14:6 | 0.853 |
| Weight (kg), mean ± SD | 13.45 ± 6.34 | 14.17 ± 5.47 | 12.67 ± 7.83 | 1.074 |
| DAS28, mean ± SD | 6.23 ± 2.34 | 6.17 ± 1.78 | – | |
| MRI (synovitis/erosion), n (%) | 16 (80) | 13 (100) | – | |
| Anti-AKA positivity, n (%) | 1 (5.0) | 7 (53.3) | – | |
| Anti-CCP positivity, n (%) | 2 (10.0) | 10 (76.9) | – | |
| RF-IgG positivity, n (%) | 15 (75.0) | 9 (69.2) | – | |
| FER (ng/mL), mean ± SD | 1079.47 ± 900.87 | 138.12 ± 45.14 | – | |
| CRP (mg/L), mean ± SD | 98.61 ± 63.80 | 89.74 ± 34.85 | 1.76 ± 0.84 | 0.001 |
| ESR (mm/h), mean ± SD | 53.12 ± 26.59 | 37.00 ± 19.32 | 2.57 ± 1.15 | 0.001 |
sJIA systemic juvenile idiopathic arthritis, pJIA polyarticular juvenile idiopathic arthritis, CCP cyclic citrullinated peptide, AKA anti-keratin antibody, FER ferritin, RF-IgG rheumatoid factor IgG, CRP C-reactive protein, ESR erythrocyte sedimentation rate, MRI magnetic resonance imaging, SD standard deviation