Table 2.
Expression of miR-21 and STAT3/SOCS3 in sJIA and pJIA group
| Group | Case group | Control (n = 20) | Z/P value | |
|---|---|---|---|---|
| sJIA (n = 20) | pJIA (n = 13) | |||
| MiR-21 | 7.70 (7.00, 8.50) | 6.49 (6.00, 7.00) | 1.02 (0.64, 1.45) | 2.615/0.015, 2.334/0.029 |
| STAT3 | 6.24 (2.81, 7.54) | 3.97 (1.81,5.75) | 1.00 (0.56, 1.29) | 4.869/0.001, 3.804/0.008 |
| TNF-α | 3.03 (2.07, 3.80) | 3.42 (2.46, 4.68) | 1.09 (0.93, 2.01) | 3.356/0.002, 5.146/0.001 |
| IL-6 | 4.75 (3.59, 6.32) | 3.52 (2.31, 7.51) | 1.87 (1.23, 2.54) | 3.082/0.006, 2.388/0.036 |
| SOCS3 | 2.54 (1.77, 4.00) | 3.57 (1.95, 3.83) | 0.86 (0.21, 1.20) | 3.344/0.003, 4.783/0.001 |
sJIA systemic juvenile idiopathic arthritis, pJIA polyarticular juvenile idiopathic arthritis, STAT3 signal transducers and activators of transcription 3, SOCS3 suppressor of cytokine signaling 3, TNF-α tumor necrosis factor-α, IL-6 interleukin-6