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Target structure and half-life of immune checkpoint inhibitors, modified according to [20]
| Target structure | Half-life | |
|---|---|---|
| Ipilimumab | CTLA-4 | 15 days |
| Atezolizumab | PD-L1 | 27 days |
| Avelumab | 6.1 days | |
| Durvalumab | 21 days | |
| Nivolumab | PD-1 | 25 days |
| Pembrolizumab | 27.3 days | |
| Cemiplimab | 19 days |
CTLA-4 cytotoxic t-lymphocyte-associated-protein 4, PD-L1 programmed cell death-1 ligand 1, PD-1 programmed cell death-1
