Table 1.
Characteristics by CKD and HTN status and univariate comparisons
| Characteristic | CKD (n = 9) | No CKD (n = 44) | p value | HTN (n = 17) | No HTN (n = 40) | p value |
|---|---|---|---|---|---|---|
| Gestational age ≥ 37 weeks, n (%) | 7 (78) | 35 (79) | 0.90 | 13 (76) | 33 (82) | 0.59 |
| Weight at surgery, kg, mean (SD) | 3.2 (1) | 3.2 (1) | 0.96 | 3.3 (0.6) | 3.2 (1) | 0.89 |
| Age at surgery, days, median (IQR) | 7 (6) | 10 (11) | 0.17 | 10 (9) | 9.5 (12) | 0.79 |
| Preoperative mechanical ventilation, n (%) | 7 (78) | 31 (70) | 0.65 | 14 (82) | 28 (70) | 0.33 |
| Preoperative eGFR, mL/min/1.73 m2, median (IQR) | 51 (41) | 46 (27) | 0.55 | 46 (27) | 45 (34) | 0.91 |
| Sex, male, n (%) | 4 (44) | 30 (68) | 0.17 | 13 (76) | 24 (60) | 0.23 |
| Surgical category, n (%) | 0.04 | 0.82 | ||||
| RACHS-1 category 1 | 1 (11) | 2 (4) | 1 (6) | 2 (5) | ||
| RACHS-1 category 2 | 2 (22) | 10 (23) | 3 (18) | 9 (23) | ||
| RACHS-1 category 3 | 2 (22) | 25 (57) | 8 (47) | 22 (55) | ||
| RACHS-1 category 4 | 1 (11) | 5 (11) | 2 (11) | 4 (10) | ||
| RACHS-1 category 5 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
| RACHS-1 category 6 | 3 (34) | 2 (4) | 3 (18) | 3 (7) | ||
| Cyanotic postoperatively, n (%) | 7 (78) | 7 (16) | < 0.001 | 5 (30) | 10 (25) | 0.63 |
| Postoperative nephrotoxic medicationa use in ICU, n (%) | 3 (33) | 18 (41) | 0.67 | 6 (35) | 16 (40) | 0.73 |
| Postoperative mechanical ventilation, days, median (IQR) | 7 (5) | 6 (5) | 0.57 | 7 (6) | 6 (5) | 0.75 |
| Postoperative ICU stay >1 week, n (%) | 2 (22) | 25 (56) | 0.06 | 11 (69) | 20 (50) | 0.31 |
| Length of postoperative hospital stay, days, median (IQR) | 17 (16) | 22 (19) | 0.34 | 31 (21) | 26 (14) | 0.01 |
aNephrotoxic medication: NSAIDs, aminoglycosides, acyclovir/ganciclovir, amphotericin, vancomycin