Table 2.
Baseline patients’ characteristics
| Baseline variable | Total group (n = 430) | % | Clean group (n = 338) | % |
|---|---|---|---|---|
| Age(years) | ||||
| Mean (range) | 74.1 (50–92) | 74.3 (51–92) | ||
| Height (m) | ||||
| Mean (range) | 1.71 (1.56–1.95) | 1.71 (1.56–1.89) | ||
| Weight (kg) | ||||
| Mean (range) | 78.3 (48–140) | 78.5 (48–140) | ||
| BMI | ||||
| Mean (range) | 26.8 (14.9–46.2) | 26.9 (14.9–46.2) | ||
| Gleason score | ||||
| Mean (range) | 8 (5–10) | 8 (5–10) | ||
| 5 | 3 | 0.7 | 3 | 0.9 |
| 6 | 22 | 5.1 | 20 | 5.9 |
| 7 | 108 | 25.1 | 86 | 25.4 |
| 8 | 99 | 23.0 | 77 | 22.8 |
| 9 | 110 | 25.6 | 87 | 25.7 |
| 10 | 9 | 2.1 | 9 | 2.7 |
| Unknown | 79 | 18.4 | 56 | 16.6 |
| ECOG performance status | ||||
| Mean (range) | 0.8 (0–3) | 0.8 (0–3) | ||
| 0 | 181 | 42.1 | 148 | 43.8 |
| 1 | 152 | 35.3 | 117 | 34.6 |
| ≥ 2 | 97 | 22.6 | 73 | 21.6 |
| No. of previous systemic treatment | ||||
| 0 | 65 | 15.1 | 45 | 13.3 |
| 1 | 117 | 27.2 | 87 | 25.7 |
| 2 | 74 | 17.2 | 50 | 14.8 |
| ≥ 3 | 78 | 18.1 | 60 | 17.8 |
| Skeletal burden | ||||
| ≤ 6 mets | 98 | 22.8 | 88 | 26.0 |
| 6–20 mets | 266 | 61.9 | 193 | 57.1 |
| ≥ 20 mets | 66 | 15.3 | 57 | 16.9 |
| Baseline Hb | ||||
| Median (range) | 12.3 (9.6–15.9) | 12.4 (9.6–15.9) | ||
| < 12 g/dl | 177 | 41.2 | 131 | 38.8 |
| ≥ 12 g/dl | 253 | 58.8 | 207 | 61.2 |
| Baseline tALP | ||||
| Median (range) | 145 (11.6–1798.0) | 130 (11.6–1798.0) | ||
| < 226 U/l | 295 | 68.6 | 247 | 73.1 |
| ≥ 226 U/l | 135 | 31.4 | 91 | 26.9 |
| Baseline PSA | ||||
| < 20 ng/ml | 140 | 32.6 | 115 | 34.0 |
| ≥ 20 ng/ml | 290 | 67.4 | 223 | 66.0 |