Fig. 6.

The distribution of ELOVL4 is normal in the SCA34-KI rat retina. a–c ELOVL4 immunolabeling in the retina of P45 WT, HET, and MUT rats is present in the photoreceptor cells, as appropriate. The ELOVL4 antibody recognizes an epitope that is conserved in WT and W246G mutant ELOVL4. d–f Normal distribution of ELOVL4 immunolabeling is preserved in the photoreceptors in WT, HET, and MUT rats at 6–7 months of age (6–7 Mo). PRL, photoreceptor layer; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GCL, ganglion cell layer. Scale bars = 50 μm