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Post-fixed tissues immunostained for endogenous murine immunoglobulins (a–f) show only a regional decrease in IgG permeability for TGN-020-treated animals, both as the average diameter of positive vessels (g) and as the number of positive vessels (h). The average value per animal was considered for analysis. Mean ± SD; ∗P < 0.05, ∗∗P < 0.01. N = 5 animals for the TGN-020 group and 3 animals for the control group
