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. 2020 Sep 11;11:2176. doi: 10.3389/fimmu.2020.02176

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Copyright © 2020 Lu, Zhou, Gao, Zhou, Li, Zhang, Wang and Gui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evolutionary analyses of multiple divergent cxcr4 genes. (A) Phylogenetic tree of Cxcr4 proteins. (B) Genomic structures of cxcr4 genes. Exons and introns are shown by boxes and horizontal lines, respectively. ORFs are highlighted by black boxes. Exon and intron size are indicated above or below as bp. (C) Syntenic alignment of chromosomal regions around cxcr4 genes. Chromosome segments are represented as thick lines. Conserved gene blocks are shown in matching colors and transcription orientations are indicated by arrows. Chr, chromosome.