Table 2.
Frequency of nGBM patient population with metabolic syndrome factors (N = 146) and correlation of MetS diagnostic criteria with OS in patients with and without nGBM
| All Individuals | Individuals Who Received Surgery, Concurrent Radiation, and Temozolomide | |||||
|---|---|---|---|---|---|---|
| N | Median survival, mo (adjusted for age) (95% CI) | P valuea | N | Median survival, mo (adjusted for age) (95% CI) | P-valuea | |
| Elevated blood sugar | ||||||
| Elevated blood sugar | 40 | 7.2 (4.3–12.4) | 0.0976 | 23 | 11.9 (9.3–14.2) | 0.0298 |
| Blood sugar not elevated | 105 | 12.6 (10.4–15.6) | 67 | 17.2 (13.6–22.1) | ||
| Hypertension | ||||||
| Hypertensive | 92 | 7.4 (5.9–11.1) | 0.001 | 49 | 12.9 (11.9–15.6) | 0.1945 |
| Not hypertensive | 54 | 18.2 (13.6–22.1) | 42 | 19.7 (16.0–23.0) | ||
| Triglycerides | ||||||
| Increased triglycerides | 52 | 7.0 (5.3–12.4) | 0.0640 | 31 | 12.4 (9.3–14.2) | 0.0945 |
| Triglycerides not increased | 92 | 12.9 (11.1–16.9) | 59 | 17.9 (14.0–22.1) | ||
| HDLC | ||||||
| Decreased HDLC | 57 | 9.4 (6.0–12.9) | 0.8840 | 33 | 13.2 (12.4–25.7) | 0.9633 |
| No decreased HDLC | 83 | 12.4 (10.4–16.0) | 54 | 16.0 (13.3–19.9) | ||
| Obesity | ||||||
| Obese | 44 | 11.5 (7.8–13.6) | 0.7600 | 30 | 12.9 (11.1–19.7) | 0.1763 |
| Not obese | 101 | 11.6 (7.5–13.3) | 60 | 15.0 (12.8–22.1) | ||
a P-value for trait in Cox proportional hazards model adjusted for age at diagnosis.