Table 4.
Independent predictors of work outcomes from multivariable models
| Left work, OR (95% CI) |
Sick-leave, OR (95% CI ) |
No presenteeism, OR (95% CI) |
Presenteeism Score, IRR (95% CI) |
|||||
|---|---|---|---|---|---|---|---|---|
| Baseline predictor | MTX-starters (N = 463) | Biologic-starters (N = 260) | MTX-starters (N = 404) | Biologic-starters (N = 217) | MTX-starters (N = 325) | Biologic-starters (N = 207) | MTX-starters (N = 325) | Biologic-starters (N = 207) |
| AgeAQ10 | 1.00 (0.96, 1.03) | 1.04 (0.99, 1.11) | 0.98 (0.96, 1.01) | 1.00 (0.96, 1.04) | 1.02 (0.98, 1.06) | 1.02 (0.99, 1.05) | 1.00 (0.99, 1.01) | 1.00 (0.99, 1.02) |
| Women vs men | 1.31 (0.66, 2.63) | 0.79 (0.32, 2.00) | 1.21 (0.71, 2.08) | 0.68 (0.30, 1.56) | 1.40 (0.63, 3.08) | 1.45 (0.76, 2.78) | 1.27 (1.01, 1.60) | 1.03 (0.79, 1.34) |
| Smoking status vs never | ||||||||
| Former | 1.01 (0.45, 2.24) | 0.66 (0.27, 1.63) | 0.83 (0.49, 1.40) | 1.08 (0.51, 2.28) | 0.66 (0.34, 1.27) | 1.74 (0.89, 3.42) | 0.94 (0.78, 1.13) | 1.10 (0.89, 1.36) |
| Current | 3.47 (1.65, 7.31) | 0.84 (0.28, 2.54) | 1.01 (0.53, 1.93) | 1.02 (0.38, 2.70) | 0.44 (0.16, 1.21) | 1.58 (0.63, 3.95) | 0.96 (0.77, 1.20) | 0.95 (0.70, 1.28) |
| HAQ | 1.55 (0.85, 2.84) | 3.46 (1.39, 8.62) | 1.46 (0.90, 2.34) | 2.41 (1.12, 5.22) | 0.63 (0.34, 1.18) | 0.42 (0.21, 0.84) | 1.08 (0.92, 1.28) | 1.40 (1.13, 1.74) |
| Pain-VAS | ||||||||
| Natural scale | 1.00 (0.98, 1.01) | 0.98 (0.96, 1.00) | 1.00 (0.99, 1.01) | 1.00 (0.98, 1.01) | 1.01 (0.99, 1.03) | 1.01 (0.99, 1.03) | 1.00 (0.997, 1.01) | 1.00 (0.99, 1.00) |
| Standardized scale | 0.90 (0.58, 1.39) | 0.65 (0.41, 1.04) | 0.96 (0.68, 1.35) | 0.90 (0.59, 1.38) | 1.33 (0.83, 2.11) | 1.28 (0.85, 1.93) | 1.05 (0.92, 1.20) | 0.99 (0.88, 1.12) |
| Fatigue-VAS | ||||||||
| Natural scale | 1.00 (0.98, 1.01) | 0.99 (0.97, 1.01) | 1.01 (0.999, 1.02) | 1.00 (0.98, 1.02) | 0.98 (0.96, 1.00) | 1.01 (0.99, 1.02) | 1.01 (1.00, 1.01) | 1.01 (0.999, 1.01) |
| Standardized scale | 0.88 (0.56, 1.35) | 0.71 (0.42, 1.19) | 1.35 (0.97, 1.89) | 1.05 (0.66, 1.69) | 0.54 (0.34, 0.86) | 1.20 (0.81, 1.78) | 1.17 (1.01, 1.35) | 1.15 (0.98, 1.34) |
| HADS General distress | 1.05 (1.00, 1.10) | 1.04 (0.97, 1.11) | 1.04 (1.00, 1.08) | 1.04 (0.98, 1.09) | 0.95 (0.88, 1.02) | 0.94 (0.89, 0.99) | 1.01 (0.99, 1.02) | 1.00 (0.99, 1.02) |
| NS-SEC | ||||||||
| Class 2 vs class 1 | 1.28 (0.56, 2.92) | 0.57 (0.20, 1.65) | 0.67 (0.37, 1.21) | 1.58 (0.66, 3.80) | 1.11 (0.53, 2.36) | 1.12 (0.48, 2.63) | 0.85 (0.69, 1.05) | 1.22 (0.97, 1.55) |
| Class 3 vs class 1 | 2.14 (1.01, 4.54) | 0.46 (0.15, 1.37) | 1.39 (0.80, 2.40) | 1.54 (0.65, 3.65) | 0.92 (0.45, 1.87) | 2.08 (0.90, 4.80) | 1.07 (0.89, 1.29) | 1.20 (0.94, 1.53) |
| Comorbidity | ||||||||
| 1 comorbidity vs 0 | 0.81 (0.40, 1.66) | 0.89 (0.34, 2.29) | 1.16 (0.70, 1.92) | 0.97 (0.43, 2.16) | 0.92 (0.49, 1.73) | 0.82 (0.39, 1.71) | 1.03 (0.85, 1.23) | 1.05 (0.83, 1.33) |
| ≥2 comorbidities vs 0 | 1.58 (0.72, 3.48) | 1.12 (0.33, 3.76) | 1.06 (0.55, 2.07) | 0.92 (0.32, 2.66) | 0.99 (0.37, 2.68) | 0.36 (0.13, 0.98) | 1.01 (0.79, 1.28) | 1.01 (0.77, 1.33) |
HADS: Hospital Anxiety and Depression Scale; IRR: incidence rate ratio; NS-SEC: The National Statistics Socio-Economic Classification (see Table 2 for definition of classes); OR: odds ratio; VAS: visual analogue scale; Natural scale: the unadjusted scores from the visual analogue scales ranging from 0–100.