Table 2.
Analytical performance of assays for detection of 3GC-resistant Enterobacterales isolates in positive blood cultures.
| Method | Result | 3GC cephalosporins | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Accuracy (95% CI) | Youden | |
|---|---|---|---|---|---|---|---|---|---|
| Resistant (n = 92) | Susceptible (n = 58) | ||||||||
| BL-REDTM | Positive | 43 | 0 | 46.7% (36.9–56.9) | 100% (93.8–100) | 100% (91.8–10) | 54.2% (44.8–63.3) | 67.3% | 46.7% |
| Negative | 49 | 58 | |||||||
| β-LACTATM | Positive | 48 | 0 | 52.2% (42.1–62.1) | 100% (93.8–100) | 100% (92.6–100) | 56.9% (47.2–66.1) | 70.7% | 52.2% |
| Negative | 44 | 58 | |||||||
PPV, positive predictive value; NPV, negative predictive value.