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. 2020 Sep 11;11:578011. doi: 10.3389/fgene.2020.578011

FIGURE 2.

FIGURE 2

Effects of combined histone deacetylases inhibitors (pan- or selective HDACis) with different antitumor therapies on tumor cells. The diverse combinations with HDACis showed synergistic antitumor effects leading to a wide spectrum of biologic effects such as DNA damage, apoptosis induction, inhibition of proliferation and cellular stress. Figure created with BioRender.com.