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. 2020 Sep 11;11:578011. doi: 10.3389/fgene.2020.578011

TABLE 2.

Summary of chemical structures and selectivity profiles of HDAC inhibitors.

Class HDACis Specificity
Hydroxamates Trichostatin A I, II, and IV
SAHA/Vorinostat I, II, and IV
Belinostat I, II, and IV
Panabinostat I, II, and IV
Givinostat I, II, and IV
Abexinostat I, II, and IV
Resminostat I, II, and IV
Quisinostat I, II, and IV
Riconilostat HDAC 6
Practinostat I, II, and IV
Tefinostat I
MPT0E028 HDAC 1, 2, and 6
CHR-3996 I
CUDC-101 I, II
CUDC-907 I, II
Cyclic peptides Romidepsin I
Short chain fatty acids Sodium butyrate I, II
Phenylbutyrate I, II
Valproic acid I, II
AR-42 I, II
Pivanex I, II
AN-9 I, II
Benzamides Entinostat I, II
Mocetinostat I, IV
Tacedinaline I
4SC-202 I
Chidamide HDAC 1, 2, 3, and 10
CI944 HDAC 1 and 3
Sirtuin inhibitors Nicotinamide III
Sirtinol SIRT 1 and 2
EX527 SIRT 1 and 2
Cambinol SIRT 1 and 2