Chemical Formula: $\genfrac{}{}{0pt}{}{\text{arg min}E({\overrightarrow{F}}_i)=\sum _{k=1,2,\dots ,K}\sum _{j\in \left\{n_{i1},n_{i2},\dots ,n_{\mathit{ir}}\right\}}{({\log }_2{y}_{\mathit{ik}}-{\log }_2{y}_{ik,obs})}^2}{+\mathrm{\lambda }\sum _{j\in \left\{n_{i1},n_{i2},\dots ,n_{\mathit{ir}}\right\}}{({\log }_2{F}_{\mathit{ji}})}^2,}$