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. 2020 Sep 11;8:563607. doi: 10.3389/fcell.2020.563607

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Copyright © 2020 Lučin, Jug Vučko, Karleuša, Mahmutefendić Lučin, Blagojević Zagorac, Lisnić, Pavišić, Marcelić, Grabušić, Brizić and Lukanović Jurić.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Membranous organelle reorganization in cells infected with the recombinant MCMV with deleted genes that mediate cell rounding. Balb 3T3 cells were infected with Δ9-MCMV (with deleted M23-M26 genes) and analyzed at 16 (A) and 30 hpi (B) for subcellular localization of selected ERC markers and IE1 and M55 proteins. M55* staining indicates subcellular localization of the M55 gene product and FcR binding by m138/fcr1 gene product, which was not deleted in Δ9-MCMV. Note that fcr1 binds murine IgG₂_a but not rabbit IgG. Cell borders are indicated by fine dashed lines. Lower panel images in (B) represent the boxed area acquired at higher magnification. Bars, 10 μm. 2-column fitting image.