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. 2020 Sep 25;160(1):287–301.e20. doi: 10.1053/j.gastro.2020.09.029

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© 2021 by the AGA Institute.

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Supplementary Figure 1 — TMPRSS2 and ACE2 distribution and localization in the intestine in children and adults. Representative immunofluorescence images of ACE2 (green) and TMPRSS2 (red) counterstained with DAPI (blue) in intestinal biopsies of non-IBD patients. Magnified images of surface epithelium (se) and crypt epithelium (ce) showing only TMPRSS2 and DAPI. (A) Duodenal biopsies. (B) Terminal ileum biopsies. (C) Biopsies from indicated colonic segments. Patient age (years) and sex (M, male; F, female) indicated in the top left corner of each image. Isotype controls and no primary controls for each segment are included on the far right of each panel. Scale bar, 100 μm.