Supplementary Figure 2.

Expression of ACE2 and TMPRSS2 protein in the intestine of patients with IBD. (A) Representative immunofluorescence images of ACE2 (green) and DAPI (blue) on the left and TMPRSS2 (red) and DAPI (blue) on the right in paired inflamed and uninflamed IBD intestinal specimens. Terminal ileum from a CD patient pre-IFX (inflamed) and after IFX treatment (uninflamed). Inflamed left colon and uninflamed sigmoid colon from a patient with UC pre-biologic. Inflamed rectum from a CD patient pre-IFX and uninflamed rectum post-IFX therapy. Clinical characteristics of IBD patients and biopsies are summarized in Supplementary Table 3.