Table 2.

Predictors of in-hospital mortality at univariate and multivariate analysis.

Predictors of mortality
Predictors	Univariate		Multivariate (n = 372)
	OR (95% CI)	p-value	OR (95% CI)	p-value
Age: < 60 years	1.0 (Ref.)		1.0 (Ref.)
60–70 years	3.5 (1.3–9.6)	0.02	3.4 (1.2–9.4)	0.02
70–80 years	27.0 (11–66.2)	<0.0001	25.2 (9.8–64.4)	<0.0001
> 80 years	40.5 (16–102.6)	<0.0001	39.5 (14.7–106.5)	<0.0001
Gender: male vs female	1.3 (0.8–2.1)	p = 0.2	1.2 (0.6–2.2)	0.6
Hypertension	2.2 (1.4–3.3)	<0.0001	0.9 (0.5–1.7)	0.7
Cardiovascular diseases	3.8 (2.4–5.9)	<0.0001	1.9 (1.1–3.3)	0.02
Diabetes	2.6 (1.6–4.3)	<0.0001	1.1 (0.5–2.4)	0.7
Respiratory disease	1.9 (1–3.5)	0.04	0.8 (0.3–2.0)	0.7
Malignancy	2 (1.1–3.6)	0.02	1.0 (0.4–2.3)	0.9
Time to ED	0.95 (0.92–0.97)	<0.0001	0.98 (0.92–1-04)	0.5
ACEi	1.4 (0.8–2.5)	0.19	0.5 (0.3–1.0)	0.06
ARB	1.3 (0.7–2.4)	0.38	1.1 (0.5–2.8)	0.8
Therapy: LMWH	0.5 (0.3–0.8)	<0.001	0.4 (0.2–0.6)	<0.0001

Time to ED: time from symptoms onset to ED access. LOS: length of hospitalization. LMWH: low-molecular weight heparin; ACEi: angiotensin-converting enzyme inhibitor; ARB: angiotensin II receptor blocker.