TABLE 2.
Top GO terms and hub genes for 6 months gene modules significantly associated with 6 months cognitive function.
WGCNA Module | Associated phenotype | Top GO term (top enrichment score with FDR < 0.05) | Hub gene |
darkolivegreen | Y-maze | positive regulation of receptor recycling | Krt2 |
darkred | Y-maze | DNA topoisomerase type I activity | Cfap20 |
lightyellow | Y-maze | heterocyclic compound binding | Trio |
saddlebrown | Y-maze | establishment of protein localization to Golgi | Smim10l2a |
black | CFA | regulation of cell differentiation | Qars |
lightgreen | CFA | positive regulation of protein targeting to mitochondrion | Mccc1 |
paleturquoise | CFM | ubiquitin-ubiquitin ligase activity | Herc3 |
red | CFM | cellular response to stress | Szt2 |