Table 1. Glycosphingolipid storage disorders and accumulating lyso-GSL species.

Lysosomal storage disorder	Accumulating lyso-GSL and aliases
Gaucher disease	Glucosylsphingosine (GlcSph), lyso-glucosylceramide (LGL1), Globotriaosylsphingosine (lyso-GB3, lyso-CTH)
Fabry disease	Globotriaosylsphingosine (lyso-GB3, lyso-CTH)
Krabbe disease/globoid cell leukodystrophy/ galactosylceramide lipidosis	Galactosylsphingosine (GalSph, lyso-GalCer, psychosine)
Niemann Pick type C	Glucosylsphingosine (GlcSph, lyso-GlcCer, lyso-GL1) (Phosphorylcholinesphingosine (lyso-S(P)M))
GM1 gangliosidosis GM2 gangliosidosis (Tay Sachs, Sandhoff Disease)	Lyso-monosialoganglioside GM1 (lyso-GM1), lyso-GA1 Lyso-monosialoganglioside GM2 (lyso-GM2), lyso-GA2
Metachromatic leukodystrophy (MLD)	Sulfogalactosylsphingosine (lyso-sulfatide)