TABLE 4.
Selected clinicopathologic variables at each time in dogs with pancreatitis associated bile duct obstruction
| Variable | Time | n | Median (range) | P value |
|---|---|---|---|---|
| White blood cell count (×103) | 1 | 42 | 16.2 (4‐53.4) | .09 |
| 2 | 37 | 16.1 (4‐38.4) | ||
| 3 | 31 | 17.8 (8.3‐45.8) | ||
| 4 | 30 | 20.5 (7.4‐45.8) | ||
| 5 | 12 | 19.4 (11.4‐41.5) | ||
| Neutrophils (×103) | 1 | 42 | 12.3 (0.9‐44.3) | .03 |
| 2 | 37 | 13.1 (0.9‐35.5) | ||
| 3 | 31 | 16 (5.2‐40.3) | ||
| 4 | 30 | 17.3 (5.2‐40.3) | ||
| 5 | 12 | 16.7 (8.3‐36.1) | ||
| Band neutrophils | 1 | 38 | 0 (0‐8822) | .17 |
| 2 | 34 | 0 (0‐8822) | ||
| 3 | 30 | 0 (0‐1832) | ||
| 4 | 29 | 0 (0‐1404) | ||
| 5 | 11 | 0 (0‐758) | ||
| Platelets (×103) | 1 | 38 | 314 (12‐829) | .55 |
| 2 | 33 | 313 (12‐569) | ||
| 3 | 28 | 322.5 (0‐655) | ||
| 4 | 29 | 303 (113‐655) | ||
| 5 | 12 | 354 (224‐633) | ||
| Bilirubin (mg/dL) | 1 | 44 | 3.1 (0.1‐27.9) a,b,c | <.001 |
| 2 | 46 | 7.0 (2.2‐27.9) a,d,e | ||
| 3 | 36 | 8.9 (1.6‐27.9) b,f,g | ||
| 4 | 46 | 11.3 (2.7‐33.2) c,d,f | ||
| 5 | 29 | 2.4 (0.6‐13.7) e,g | ||
| Alkaline phosphatase (U/L) | 1 | 40 | 1502 (80‐5456)a,b,c,d | <.001 |
| 2 | 38 | 2000 (486‐10 966)a | ||
| 3 | 35 | 4155 (521‐16 056)b | ||
| 4 | 42 | 4288 (304‐14 973)c | ||
| 5 | 27 | 3202 (580‐16 655)d | ||
| Alanine aminotransferase (U/L) | 1 | 38 | 128.5 (28‐4000)a | <.001 |
| 2 | 40 | 926.5 (28‐4000)a | ||
| 3 | 35 | 1000 (139‐2702)b,c | ||
| 4 | 43 | 934 (165‐2702)b | ||
| 5 | 26 | 581 (78‐2351)c | ||
| Cholesterol (mg/dL) | 1 | 28 | 411.5 (96‐556) | .002 |
| 2 | 33 | 492 (122‐1178) | ||
| 3 | 33 | 584 (209‐1001) | ||
| 4 | 40 | 588 (207‐1001) | ||
| 5 | 26 | 459 (136‐992) | ||
| Blood urea nitrogen (mg/dL) | 1 | 44 | 14 (5‐196)a,b,c,d | <.001 |
| 2 | 45 | 9.2 (4‐196)a | ||
| 3 | 36 | 9.0 (4‐123)b | ||
| 4 | 44 | 8.0 (4‐123)c | ||
| 5 | 25 | 9.0 (4‐19)d | ||
| Creatinine (mg/dL) | 1 | 42 | 0.9 (0.5‐7.7)a | .01 |
| 2 | 41 | 0.9 (0.4‐7.7) | ||
| 3 | 36 | 0.7 (0.3‐5.3) | ||
| 4 | 43 | 0.8 (0.3–5.3)a | ||
| 5 | 25 | 0.7 (0.4‐2.2) | ||
| Albumin (mg/dL) | 1 | 40 | 3.1 (1.5‐27)a,b,c | <.001 |
| 2 | 44 | 2.7 (1.5‐4.1) | ||
| 3 | 35 | 2.8 (1.1‐3.6)a | ||
| 4 | 44 | 2.7 (1.1–3.6)b | ||
| 5 | 26 | 2.8 (1.7‐3.3)c |
Note: Superscript letters that are the same within each column indicate significant differences between time points based on Bonferroni's procedure for multiple comparisons. The level of significance is set at P ≤ .05. See Table 2 for description of time points.