Table 1.
Frequencies, estimated numbers and incidence rates of clinically diagnosed CRAO in Japan from 2011 to 2015, as determined from the National Database of the Health Insurance Claims and Specific Health Checkups of Japan
| Age group (years) | Japanese population* | Total | Male | Female | Male:female ratio |
|||||||||||||||||
| Total | Male | Female | Out patient |
Primary inpatients† | Secondary inpatients‡ | Estimated total§ | Incidence rate |
95% CI | Out patient |
Primary inpatients† | Secondary inpatients‡ | Estimated total§ |
Incidence rate |
95% CI | Out patient |
Primary inpatients† | Secondary inpatients‡ | Estimated total§ |
Incidence Rate |
95% CI | ||
| 0–4 | 5238 | 2684 | 2554 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| 5–9 | 5361 | 2743 | 2618 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| 10–14 | 5790 | 2967 | 2823 | 0 | 0 | 1 | 30 | 0.10 | 0.02 to 0.19 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 1 | 30 | 0.21 | 0.04 to 0.38 | 0 |
| 15–19 | 6047 | 3098 | 2949 | 1 | 0 | 0 | 300 | 0.99 | 0.74 to 1.24 | 1 | 0 | 0 | 300 | 1.94 | 1.45 to 2.43 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| 20–24 | 6204 | 3181 | 3023 | 0 | 0 | 1 | 30 | 0.10 | 0.02 to 0.17 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 1 | 30 | 0.20 | 0.04 to 0.36 | 0 |
| 25–29 | 6871 | 3506 | 3365 | 0 | 1 | 0 | 6 | 0.02 | −0.01 to 0.05 | 0 | 1 | 0 | 6 | 0.03 | −0.03 to 0.10 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| 30–34 | 7624 | 3867 | 3757 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| 35–39 | 9059 | 4592 | 4467 | 2 | 4 | 0 | 624 | 1.38 | 1.14 to 1.62 | 0 | 3 | 0 | 18 | 0.08 | 0.00 to 0.16 | 2 | 1 | 0 | 606 | 2.71 | 2.23 to 3.20 | 0.03 |
| 40–44 | 9667 | 4888 | 4779 | 2 | 3 | 1 | 648 | 1.34 | 1.11 to 1.57 | 2 | 1 | 0 | 606 | 2.48 | 2.04 to 2.92 | 0 | 2 | 1 | 42 | 0.18 | 0.06 to 0.29 | 14.11 |
| 45–49 | 8405 | 4228 | 4177 | 5 | 5 | 0 | 1530 | 3.64 | 3.23 to 4.05 | 3 | 4 | 0 | 924 | 4.37 | 3.74 to 5.00 | 2 | 1 | 0 | 606 | 2.90 | 2.39 to 3.42 | 1.51 |
| 50–54 | 7733 | 3870 | 3863 | 4 | 5 | 1 | 1260 | 3.26 | 2.86 to 3.66 | 0 | 2 | 1 | 42 | 0.22 | 0.07 to 0.36 | 4 | 3 | 0 | 1218 | 6.31 | 5.51 to 7.10 | 0.03 |
| 55–59 | 7732 | 3840 | 3892 | 3 | 6 | 1 | 966 | 2.50 | 2.15 to 2.85 | 1 | 4 | 1 | 354 | 1.84 | 1.41 to 2.27 | 2 | 2 | 0 | 612 | 3.14 | 2.59 to 3.70 | 0.59 |
| 60–64 | 9665 | 4740 | 4925 | 14 | 8 | 1 | 4278 | 8.85 | 8.26 to 9.45 | 8 | 3 | 1 | 2448 | 10.33 | 9.41 to 11.24 | 6 | 5 | 0 | 1830 | 7.43 | 6.67 to 8.19 | 1.39 |
| 65–69 | 8700 | 4183 | 4517 | 17 | 18 | 2 | 5268 | 112.11 | 11.38 to 12.84 | 12 | 15 | 0 | 3690 | 17.64 | 16.37 to 18.92 | 5 | 3 | 2 | 1578 | 6.99 | 6.22 to 7.76 | 2.53 |
| 70–74 | 7597 | 3537 | 4060 | 25 | 29 | 6 | 7854 | 20.68 | 19.65 to 21.70 | 15 | 20 | 3 | 4710 | 26.63 | 24.93 to 28.33 | 10 | 9 | 3 | 3144 | 15.49 | 14.28 to 16.70 | 1.72 |
| 75–79 | 6301 | 2772 | 3529 | 22 | 20 | 4 | 6840 | 21.71 | 20.56to 22.86 | 15 | 14 | 1 | 4614 | 33.29 | 31.14 to 35.44 | 7 | 6 | 3 | 2226 | 12.62 | 11.44 to 13.79 | 2.64 |
| 80–84 | 4763 | 1889 | 2874 | 12 | 17 | 4 | 3822 | 16.05 | 14.91 to 17.19 | 8 | 10 | 3 | 2550 | 27.00 | 24.66 to 29.34 | 4 | 7 | 1 | 1272 | 8.85 | 7.76 to 9.94 | 3.05 |
| 85–89 | 2925 | 970 | 1955 | 9 | 10 | 1 | 2790 | 19.08 | 17.49 to 20.66 | 3 | 6 | 0 | 936 | 19.30 | 16.53 to 22.06 | 6 | 4 | 1 | 1854 | 18.97 | 17.04 to 20.90 | 1.02 |
| 90–94 | 1216 | 283 | 933 | 3 | 6 | 0 | 936 | 15.39 | 13.19 to 17.60 | 0 | 3 | 0 | 18 | 1.27 | −0.04 to 2.59 | 3 | 3 | 0 | 918 | 19.68 | 16.83 to 22.52 | 0.06 |
| 95–99 | 350 | 61 | 289 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| >100 | 55 | 7 | 48 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | 0 | 0 | 0 | 0 | 0.00 | 0.00 | NA |
| Total | 127 303 | 61 906 | 65 397 | 119 | 132 | 23 | 37 182 | 5.84 | 5.71 to 5.97 | 68 | 86 | 10 | 21 216 | 6.85 | 6.65 to 7.06 | 51 | 46 | 13 | 15 966 | 4.788 | 4.71 to 5.05 | 1.40 |
*Japanese population data (as of 1 October 2013) were based on the Japanese Ministry of Internal Affairs and Communications (unit: 1000 people).
†Primary inpatients represent those admitted primarily for CRAO.
‡Secondary inpatients represent those who developed CRAO while hospitalised for other diseases The incidence of CRAO in outpatients, primary inpatients, secondary inpatients or estimated total are each the sum of 20 months (4 months/year×5 years).
§The estimated total CRAO patients is calculated by multiplying the number of outpatients by 300 plus 20% of the primary inpatients and 100% of secondary inpatients by 30, because the NDB sampling dataset covers 1/300 of all outpatient claims data and 1/30 of all inpatient claims data. The outpatients later becoming inpatients account for 20% of primary inpatients data. The incidence rate is reported per 100 000 person-years.
CRAO, central retinal artery occlusion; NA, not applicable.