Additional examples of H3 PTMs including H3.3S31ph (as in Fig. 2) at (A) LPS-induced genes Bcl2a1b, Ccl4, Cxcl2, Dusp1, Myc; (B) constitutively expressed (“housekeeping”) genes Gapdh, Rps2, Tbp, Tubb5, Tubb6; (C) across the gene dense chromosome 11 chemokine locus (>1Mb) containing LPS-induced genes Slfn2, Ccl9, Ccl6, Ccl3, Ccl4.