Table 3.

Metabolites associated with gestational age at delivery

Metabolite	Biochemical ID	Super pathway	Sub pathway	Estimate	SE	P value	FDR
TG17.2/36.4	TG17:2/36:4	Lipid	Triaclylgerol	− 0.4	0.1	< 0.001	0.038
DG.18.1/18.1	DG18:1/18:1	Lipid	Diacylglycerol	− 1.7	0.5	0.002	0.044
DG.18.1/18.2	DG18:1/18:2	Lipid	Diacylglycerol	− 4.4	1.2	0.001	0.044
DG.18.2/18.2	DG18:2/18:2	Lipid	Diacylglycerol	− 2.8	0.9	0.002	0.044
TG16.0/36.3	TG16:0/36:3	Lipid	Triaclylgerol	− 157.6	43.0	0.001	0.044
TG16.1/36.3	TG16:1/36:3	Lipid	Triaclylgerol	− 12.8	3.8	0.001	0.044
TG18.0/36.3	TG18:0/36:3	Lipid	Triaclylgerol	− 7.9	2.3	0.001	0.044
TG18.1/34.1	TG18:1/34:1	Lipid	Triaclylgerol	− 194.1	57.2	0.001	0.044
TG18.1/34.2	TG18:1/34:2	Lipid	Triaclylgerol	− 132.1	39.4	0.001	0.044
TG18.1/36.1	TG18:1/36:1	Lipid	Triaclylgerol	− 14.0	4.3	0.002	0.044
TG18.1/36.2	TG18:1/36:2	Lipid	Triaclylgerol	− 53.1	15.5	0.001	0.044
TG18.1/36.3	TG18:1/36:3	Lipid	Triaclylgerol	− 61.7	16.2	< 0.001	0.044
TG18.2/34.1	TG18:2/34:1	Lipid	Triaclylgerol	− 125.3	36.6	0.001	0.044
TG18.2/36.0	TG18:2/36:0	Lipid	Triaclylgerol	− 1.0	0.3	0.002	0.044
TG18.2/36.1	TG18:2/36:1	Lipid	Triaclylgerol	− 9.7	3.0	0.002	0.044
TG18.2/36.2	TG18:2/36:2	Lipid	Triaclylgerol	− 31.2	9.6	0.002	0.044
TG18.2/38.4	TG18:2/38:4	Lipid	Triaclylgerol	− 1.9	0.5	0.001	0.044
TG20.0/32.4	TG20:0/32:4	Lipid	Triaclylgerol	− 0.5	0.1	0.002	0.044
TG20.4/36.2	TG20:4/36:2	Lipid	Triaclylgerol	− 3.7	1.1	0.001	0.044
GCA	Glycocholic acid	Lipid	Bile Acid	− 0.2	0.1	0.002	0.046
TG18.0/36.4	TG18:0/36:4	Lipid	Triaclylgerol	− 3.8	1.2	0.002	0.046

Linear regression was performed to identify significant metabolites associated with pre-term delivery using the R statistical package after correcting for age, BMI and principle components (PC1 and PC2). Estimate (beta value), SE, standard error; FDR, False Discovery Rate