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. 2020 Sep 25;15:223. doi: 10.1186/s13014-020-01662-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Hematoxylin-eosin staining showed changes to the spiral ganglion cells and hair cells of the utriculus and sacculus after irradiation and resolvin E1-pretreatment. The arrows indicate the points of the loss of spiral ganglion cells and utriculus and sacculus hair cells, and the number of arrows represents the frequency of damage, which could be observed on days 7 and 14 after irradiation. Meanwhile, pretreatment with resolvin E1 mitigated the damage. The loss of utriculus and sacculus hair cells represents that of vestibular hair cells