Table 6:
Linear Regression Models Predicting Duration of ECMO in ECMO survivors (N=237)
| Fluid Overload at CRRT Initiation | |||
|---|---|---|---|
| Variable | Relative Change | 95% CI | p-value |
| Fluid Overload at CRRT Initiation * | 1.033 | (1.007 – 1.060) | 0.01 |
| Pediatric** | 1.062 | (0.895 – 1.259) | 0.49 |
| ECMO Mode VV *** | 0.965 | (0.773 – 1.205) | 0.76 |
| Support type: Cardiac**** | 0.629 | (0.501 – 0.789) | <0.0001 |
| Support type: ECPR**** | 0.597 | (0.461 – 0.773) | 0.0001 |
| Non-Renal Patient Complications | 1.957 | (1.282 – 2.987) | 0.002 |
| pH at initiation | 1.280 | (0.817 – 2.004) | 0.28 |
| AKI | 1.304 | (1.079 – 1.576) | 0.01 |
| Fluid Overload at CRRT Discontinuation | |||
| Variable | Relative Change | 95% CI | p-value |
| Fluid Overload on CRRT Discontinuation * | 1.041 | (1.020 – 1.063) | 0.0002 |
| Pediatric** | 1.070 | (0.897 – 1.277) | 0.45 |
| ECMO Mode VV *** | 0.905 | (0.714 – 1.146) | 0.40 |
| Support type: Cardiac**** | 0.693 | (0.546 – 0.897) | 0.003 |
| Support type: ECPR**** | 0.632 | (0.486 – 0.823) | 0.001 |
| Non-Renal Patient Complications | 1.947 | (1.303 – 2.909) | 0.001 |
| pH at initiation | 0.940 | (0.592 – 1.492) | 0.79 |
| AKI | 1.157 | (0.955 – 1.401) | 0.13 |
| Change in Fluid Overload on CRRT | |||
| Variable | Relative Change | 95% CI | p-value |
| Change in Fluid Overload on CRRT (%) * | 1.036 | (0.998 – 1.075) | 0.06 |
| Pediatric** | 1.053 | (0.877 – 1.264) | 0.58 |
| ECMO Mode VV *** | 0.914 | (0.717 – 1.166) | 0.47 |
| Support type: Cardiac**** | 0.678 | (0.530 – 0.866) | 0.002 |
| Support type: ECPR**** | 0.607 | (0.463 – 0.795) | 0.0004 |
| Non-Renal Patient Complications | 2.015 | (1.333 – 3.045) | 0.001 |
| pH at initiation | 0.969 | (0.601 – 1.562) | 0.90 |
| AKI | 1.160 | (0.953 – 1.413) | 0.14 |
| Negative change in Fluid Overload om CRRT | |||
| Variable | Relative Change | 95% CI | p-value |
| Negative change in Fluid Overload (%) on CRRT (Y/N) * | 0.882 | (0.739 – 1.053) | 0.16 |
| Pediatric** | 1.065 | (0.887 – 1.279) | 0.50 |
| ECMO Mode VV *** | 0.917 | (0.719 – 1.171) | 0.49 |
| Support type: Cardiac**** | 0.672 | (0.525 – 0.86) | 0.002 |
| Support type: ECPR**** | 0.598 | (0.456 – 0.785) | 0.0002 |
| Patient Complications | 2.044 | (1.35 – 3.096) | 0.001 |
| pH at initiation | 0.984 | (0.61 – 1.589) | 0.95 |
| AKI | 1.174 | (0.964 – 1.43) | 0.11 |
All models adjusted for center in addition;
*
Examines per 10% rise in FO
**
Reference neonates,
***
Reference VA ECMO,
****
Reference Support type: Pulmonary