Table 6.
Odds of clinical malaria and asymptomatic Pf infection by compound serological status. Estimates are weighted by compound size and shown as unadjusted odds ratios (OR) and adjusted odds ratios (aOR) for age group (< 5 years, 5–15 years, and > 15 years)
| Odds of clinical malaria or asymptomatic Pf infection for individuals residing in sero-positive compounds | ||||||
|---|---|---|---|---|---|---|
| Unadjusted | Adjusted | |||||
| OR | 95% CI | p value | aOR | 95% CI | p value | |
| Etramp5.Ag1 | ||||||
| Clinical malaria | 0.19 | 0.03–1.06 | 0.059 | 0.17 | 0.03–0.89 | 0.036 |
| Asymptomatic infection | 2.83 | 1.62–4.96 | < 0.001 | 2.87 | 1.62–5.07 | < 0.001 |
| GEXP18 | ||||||
| Clinical malaria | 0.13 | 0.02–0.90 | 0.039 | 0.11 | 0.02–0.73 | 0.022 |
| Asymptomatic infection | 2.65 | 1.58–4.47 | < 0.001 | 2.61 | 1.54–4.42 | < 0.001 |
| HSP40.Ag1 | ||||||
| Clinical malaria | 0.14 | 0.02–0.80 | 0.027 | 0.13 | 0.02–0.70 | 0.018 |
| Asymptomatic infection | 1.32 | 0.77–2.28 | 0.316 | 1.38 | 0.79–2.41 | 0.257 |
| Rh2.2030 | ||||||
| Clinical malaria | 0.07 | 0.01–0.48 | 0.006 | 0.06 | 0.01–0.35 | 0.002 |
| Asymptomatic infection | 1.69 | 0.96–2.99 | 0.070 | 1.92 | 1.10–3.36 | 0.022 |
| EBA175 | ||||||
| Clinical malaria | 0.07 | 0.01–0.61 | 0.016 | 0.07 | 0.01–0.57 | 0.013 |
| Asymptomatic infection | 1.00 | 0.50–2.01 | 0.992 | 1.02 | 0.50–2.09 | 0.954 |
| PfMSP119 | ||||||
| Clinical malaria | 0.15 | 0.03–0.87 | 0.034 | 0.12 | 0.03–0.50 | 0.004 |
| Asymptomatic infection | 1.87 | 1.15–3.06 | 0.012 | 1.95 | 1.19–3.20 | 0.008 |
| PfAMA1 | ||||||
| Clinical malaria | 0.06 | 0.01–0.62 | 0.018 | 0.05 | 0.01–0.52 | 0.011 |
| Asymptomatic infection | 1.96 | 1.01–3.81 | 0.046 | 1.99 | 1.00–3.93 | 0.048 |
| PfGLURP.R2 | ||||||
| Clinical malaria | 0.06 | 0.01–0.53 | 0.012 | 0.05 | 0.01–0.43 | 0.006 |
| Asymptomatic infection | 1.59 | 0.85–2.97 | 0.145 | 1.52 | 0.77–3.01 | 0.228 |