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. 2020 Sep 24;11:54. doi: 10.1186/s13293-020-00331-6

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Ischemia reperfusion (IR) during pregnancy increases hypertension and parameters of HELLP in NP rats. Mean arterial pressure was significantly increased in HELLP and HELLP+AKI rats (a). HELLP and NP rats subjected to IR had increased lactate dehydrogenase (b) and aspartate aminotransferase (c) and decreased platelet counts (d). The weight of both kidneys per animal was averaged (grams), and the ratio of kidney/body weight (grams) was determined (e) as was the average weight of pups per group (f). *^–****p < 0.05–p < 0.00005 between indicated groups. N = 13–15/group