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. 2020 Sep 25;22:223. doi: 10.1186/s13075-020-02291-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Relation between serum and whole-blood level of hydroxychloroquine (HCQ) in SLE patients with whole-blood levels < 300 ng/mL. The green and violet lines represent the HCQ level cut-off for non-adherence in serum (106 ng/mL) and whole blood (200 ng/mL), respectively. The orange square represents 14 patients who had both serum and whole-blood HCQ levels below the lower limit of quantification (20 ng/mL). Red crosses represent severe non-adherent patients with whole-blood HCQ levels between 20 and 200 ng/mL. Blue crosses represent patients with whole-blood HCQ levels between 200 and 300 ng/mL