FIGURE 2.
Food anticipatory behavior in Tryptophan hydroxylase 2 knockout mice. (A) Mean ± SEM seconds of high activity behaviors (hanging, jumping, rearing, and walking) on the first day (“day 0”) of scheduled CR feeding. (A’) Normalized mean ± SEM high activity of data shown in (A). (B) Mean ± SEM seconds of high activity behaviors after 7 days of timed CR feeding. (B’) Normalized mean ± SEM high activity of data shown in (B). (C) Mean ± SEM seconds of high activity behaviors after 14 days of timed CR feeding. (C’) Normalized mean ± SEM high activity of data shown in (C). (D) Mean ± SEM seconds of high activity behaviors after 21 days of timed CR feeding. (D’) Normalized mean ± SEM high activity of data shown in (D). (E) Mean ± SEM seconds of high activity data in the 3 h preceding scheduled feeding across the experiment. (E’) Mean ± SEM normalized high activity data in the 3 h preceding scheduled feeding across the experiment. n = 12–15 WT and n = 10–16 KO per time point.