. 2020 Sep 7;34(5):1801–1812. doi: 10.1111/jvim.15895

TABLE 5.

Significant correlations (r > .5) between pancreatic lipases, protease inhibitors, hemostatic analytes, C‐reactive protein, and cytokines in 31 dogs with acute pancreatitis

Analyte	Correlated with	r ^a	P value
cPLI₀	IL‐6₁	.75	0
cPLI₀	CRP₀	.52	.005
cPLI₁	IL‐6₀	.55	.003
	IL‐6₁	.68	0
	IL‐6_max	.57	.001
	Ionized calcium	−.62	.009
CRP₀	IL‐6₁	.58	.001
	cholesterol	.68	0
	TG	.52	.023
CRP₁	IL‐6₁	.65	0
	IL‐6_max	.51	.006
	Ionized calcium	−.67	.003
CRP_max	IL‐6₁	.58	.001
	IL‐6_max	.62	0
	Ionized calcium	−.58	.009
	Cholesterol	.58	.001
IL‐2₀	IL‐6₀	.65	0
	IL‐6_max	.56	.001
	IL‐8₀	.92	0
	IL‐8₁	.60	.001
	IL‐8_max	.74	0
	TNFα₁	.53	.004
IL‐2₁	IL‐8₁	.89	.000
	IL‐8_max	.84	.000
	TNFα₀	.504	.007
	TNFα₁	.80	0
	TNFα_max	.84	0
	Hemoglobin	−.52	.007
	Hematocrit	−.53	.005
IL‐2_max	IL‐6₁	.61	.001
	IL‐8₀	.67	0
	IL‐8₁	.89	0
	IL‐8_max	.82	0
	TNFα₁	.839	0
	Hematocrit	−.53	.003
IL‐6₁	Ionized calcium	−.73	.001
IL‐6₁	Amylase	.62	.001
IL‐8₀	TNFα₁	.60	.001
IL‐8₁	TNFα₀	.59	.001
	TNFα₁	.86	.000
	TNFα_max	.93	0
α₁PI₀	Duration of clinical signs	−.50	.002
α₂antiplasmin₀	Duration of clinical signs	−.52	.007

Notes: Subscripts 0, 1 max and min refer to concentrations on day 0 (presentation), day 1 (1 day post‐presentation), maximal and minimal concentrations during days 0 and 1, respectively.

Abbreviations: _α1PI, α₁‐proteinase inhibitor concentration; clinical signs duration, lag of time from onset of clinical signs to presentation to the hospital; cPLI, canine pancreatic‐like immunoreactivity; CRP, C‐reactive protein; IL, interleukin; TNFα, tumor necrosis factor α.

^{^a}

Spearman's correlation tests were done when ≥1 of the tested variables had non‐normal distribution, whereas Pearson's correlation tests were done when both tested variables were distributed normally.